Lifelong antiplatelet therapy is recommended after PFO closure. PFO closure is recommended if there is no other reason for the stroke was found in patients with PFO.

3-5 field higher  in cryptogenic a stroke.  High risk’’ PFO features include: Atrial septal aneurysm, spontaneous right-to-left shunting, tunnel- appearance & deep divers who wants to continue diving should be considered also. In people below 55 years of age who have cryptogenic stroke could have PFO.

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