Lupus anticoagulants

Lupus anticoagulant

S/S inc thrombosis / spontaneous abortion.
Dx: prolong ptt, + phospholipid neutralization assay, + platelet neutralization assay, prolonged diluted viper venom time,
C: inc in infection, inflammation, cancer,
Rx aim INR 2-3, during pregnancy use low molecular wt heparin.

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