Reyvow. (Lasmiditan) 50-100-200 mg

👉Abortive. Acute Migraine attack.

👉50 ;   100;  200 mg tab.

👉50-200 mg : 1 dose /d.

👉Do not cut, crush, chew.

👉Do NOT drive for 8 hrs post dose.

👉No alcohol or sedative w it. 

👉5-HT1F receptor, inhibit trigeminal n firing. 

👉3% unchanged in urine

👉HL 5.7 hrs

👉SE: Dizziness, Sedation, Fatigue, Nausea, Vomiting, Paresthesia, Weakness

👉 HR; BP; CNS depression, Serotonin synd, HA > 10 d /month use

👉No preg / no lactation human data available

👉Interactions: w CNS depressants, serotonergic meds, BCRP inhibitors (chemo), P-gp inhibitors (meds causing bradycardia)

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