Ajovy

Ajovy
Fremanezumab
Monoclonal antibody
Blocks CGRP
Migraine prophylaxis
Auto-injector : 225 mg in 1.5 ml
225 mg SC 1 dose / month or 3 q 3 months
No drug interactions, no contraindications except allergic to any ingredients
SE : rash, pruritus, injection site/hypersensitive reaction, constipation
No pregnancy or lactation Data available
no safety monitoring recommend
Peak 1 week
HL : 1 month (31 d)
Steady state 6 months
Metabolism by enzymatic Proteolysis