WNV: West Nile virus : ♦️Distinguishing symptoms: tremors, Parkinsonism, myoclonus +

👉80% Asymptotic 👉20% Fever👉Headache, body ache, joint pain, nausea, diarrhea, rash, 👉Fatigue, Fever, weakness lasts months👉1 in 150 : encephalitis, meningitis, 👉Severe S/S : all of the above much intensified, fever, HA, neck stiffness, weakness, vision loss, tremors up to 100%, Parkinson’s s/s, myoclonus, convulsions, paralysis, disorientation, coma. Any age but more common > 60. immunocompromised. ♦️♦️Distinguishing symptoms: tremors, Parkinsonism, myoclonus ( very characteristic of WNV than others.🚦1 in 10 die. 👉Recovery: weeks / months. Some developed permanent Neurologic issues.g👉WNV IgM serum / CSF antibodies. Takes 3-8 d, repeat if negative. IgG last long time for years suggest prior infection. Confirm w neutralizing antibody testing. 👉Viral cultures / viral RNA (RT-PCR reverse transcriptase-polymerase chain reaction can be performed on serum, CSF & tissue specimens collected early for + confirm👉Complications: Rare: dysrhythmias, myocarditis, rhabdomyolysis, optic neuritis, uveitis, chorioretinitis, orchitis, pancreatitis, hepatitis have been described in patients with WNV disease. Infants show no infection even if mothers have it.

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